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and at present, one third of our pregnant population has a BMI greater than 30.

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Another major symptom is fatigue.[3] Headaches are common, and abdominal pains with nausea or vomiting sometimes also occur.[5] Symptoms most often disappear after about 2 3 weeks.[3][8] However, fatigue and a general feeling of being unwell may sometimes last for months.[6] Fatigue lasts more than one month in an estimated 9 22% of cases.[3] In cases where fatigue lingers, it generally passes spontaneously within 2 years.[3] Mild fever, swollen neck glands and body aches may also persist beyond 4 weeks.[6][9][10] Most people are able to resume their usual activities within 2 3 months.[9]

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In the UK, John McLaren Howard analyses a very extensive range of chemical and metal genomic DNA adducts in leucocytes. He finds toxic DNA adducts in some women taking hormones, some cancer patients and some autistic children. Commonest adducts are malondialdehyde, probably from lipid peroxidation secondary to poor superoxide dismutase activity and copper/zinc upsets; also nickel complex on the hormone receptor enzyme adenylate cyclase gene; nickel which part blocks the expression lv mm neverfull
of cytoplasmic superoxide dismutase; and, also cadmium and mercury adducts.